Key publications

Moller-Levet C.S., Archer S.N., Bucca G., Laing E. E. Slak A., Kabiljo R., Lo J.C.Y., Santhi N., von Schantz M., Smith C.P. and Dijk D.J. Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome.  PNAS (2013) E1132-E1141

Archer S.N., Laing E. E., Moller-Levet C.S., van der Veen D.R., Bucca G., Lazar A. S., Santhi N.,, Slak A., Kabiljo R., von Schantz M., Smith C.P. and Dijk D.J.  Mistimed sleep disrupts circadian regulation of the human transcriptome. PNAS 1316335111, 1-10

Ackermann, K., Plomp, R., Lao, O., Middleton, B., Revell, V.L., Skene, D.J. and Kayser, M. Effect of sleep deprivation on rhythms of clock gene expression and melatonin in humans. Chronobiol. Int. (2013)

Ang, J.E., Revell, V., Mann, A., Mäntele, S., Otway, D.T., Johnston, J.D., Thumser, A.E., Skene, D.J. and Raynaud, F. Identification of human plasma metabolites exhibiting time-of-day variation using an untargeted liquid chromatography-mass spectrometry metabolomics approach. Chronobiol. Int. (2012) 29, 868-881

Mäntele, S., Otway, D.T., Middleton, B., Bretschneider, S., Wright, J., Robertson, M.D., Skene, D.J. and Johnston, J.D. Daily rhythms of plasma melatonin, but not plasma leptin or leptin mRNA, vary between lean, obese and type 2 diabetic men. PLoS One (2012) 7, e37123.

Ackermann, K., Revell, V.L., Lao, O., Rombouts, E.J., Skene, D.J. and Kayser, M. Diurnal rhythms in blood cell populations and the effect of acute sleep deprivation. Sleep (2012) 35, 933-940. Kerkhofs, M. and Boudjeltia, K.Z. From total sleep deprivation to cardiovascular disease: a key role for the immune system? Sleep (2012) 35, 895-896

Otway, D.T., Mäntele, S., Bretschneider, S., Wright, J., Trayhurn, P., Skene, D.J., Robertson, M.D. and Johnston, J.D. Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight and have type 2 diabetes. Diabetes (2011) 60, 1577-1581.

Dijk DJ, Groeger JA, Stanley N, Deacon S. Age-related reduction in daytime sleep propensity and nocturnal slow wave sleep. SLEEP, 2010; 33:211-223.

Cohen DA, Wang W, Wyatt JK, Kronauer RE, Dijk DJ, Czeisler CA, Klerman EB. Uncovering residual effects of chronic sleep loss on human performance. Science Translational Medicine. 2010; 2 (14) 14ra3

Dijk DJ, James LM, Peter S, Walsh JK, Deacon S. Sex differences in the effect of gaboxadol and zolpidem on EEG power spectra in NREM and REM sleep. Journal of Psychopharmacology. 2010;24:1613-8.

Iannone R, Palcza JS, Renger JJ, Calder NA, Cerchio KA, Gottesdiener KM, Hargreaves RJ, Dijk DJ, Boyle J, Murphy M. Acute Alerting Effects of a Novel Histamine Subtype-3 Receptor Inverse Agonist in Healthy Sleep-deprived Male Volunteers. Clinical Pharmacology and Therapeutics 2010;88(6):831-839.

Vandewalle G, Schwartz S, Grandjean D, Wuillaume C Balteau E, Degueldre C, Schabus M, Phillips C, Luxen A, Dijk DJ, Maquet P. The spectral quality of light modulates emotional brain responses in humans. Proceedings National Academy of Sciences, USA 2010;107(45):19549-19554

Dijk DJ, Archer SN. PERIOD3, Circadian Phenotypes, and Sleep Homeostasis. Sleep Medicine Reviews, 2010, 14:151-60.

Dijk DJ. Slow-wave sleep deficiency and enhancement: implications for insomnia and its management. World J Biol Psychiatry. 2010 Jun;11 Suppl 1:22-8. Review

Wilson SJ, Nutt DJ, Alford C, Argyropoulos SV, Baldwin DS, Bateson A, Britton T, Crowe C, Dijk DJ, Espie C, Gringras P, Hajak G, Idzikowski C, Krystal A, Nash JR, Selsick H, Sharpley AL, Wade AG. British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. J Psychopharmacol. 2010 Sep 2. ahead of print

Dijk DJ Slow-wave sleep: characteristics and homeostatic regulation In Slow-wave sleep: beyond insomnia: The importance of slow-wave sleep for your patients Roth T & Dijk DJ (editors) Wolters Kluwer Pharma Solutions, London 2010. ISBN 978-0-9561387-1-2, 155 pp

Landolt HP and Dijk DJ Genetic basis of sleep in healthy humans. In Principles and Practice of Sleep Medicine. 5th Edition. MH Kryger, T. Roth, WC Dement (eds). Elsevier, Saunders; St Louis, Missouri. 2010, pp 175-183.